Dionex™ ICS-6000 Hybrid HPIC™ System

Get best-in-class resolution, sensitivity, and throughput for even the most complex ICxIC (2D-IC) methods and trace level analyses. The versatile Thermo Scientific™ Dionex™ ICS-6000 Hybrid HPIC™ Systems provide faster separations without compromising resolution, thanks to its dual high-pressure channels. One channel is optimized for capillary flow rates, while the other is optimized for standard (4mm) or microbore (2mm) mode. You’ll save time and improve reproducibility with precise, automatic eluent generation and sample preparation. Choose from a wide variety of chemistries, detectors, and automation options to fit your needs.

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    Built on our top-of-the-line IC platform, this system provides the high performance, convenience, and flexibility of the Thermo Scientific™ Dionex™ ICS-6000 HPIC System with the power of parallel analytical and capillary channels.

    Dual system advantage

    Run two analyses concurrently on a single sample, analyze two samples, or perform advanced ICxIC (2D-IC) techniques. The Dionex ICS-6000 Hybrid HPIC System is ideally suited for trace level determinations with high matrix concentrations, using a standard or microbore column in the first dimension to separate analytes from matrix, followed by a capillary separation in the second dimension. This method provides high sensitivity, enabling conductivity detection limits to rival those of mass spectrometry.

    Choose from three dual-channel configurations

    • Dionex ICS-6000 RFIC Standard Bore-Capillary System
    • Dionex ICS-6000 RFIC Microbore-Capillary HPIC System
    • Dionex ICS-6000 BioIC ED Capillary-Microbore HPIC System for carbohydrates (capillary) and AAA-Direct (microbore) applications

    High pressure, high performance IC

    • Fast, sensitive separations without sacrificing resolution—up to two times faster still with Fast IC columns
    • Outstanding resolution using columns with small-diameter particles, thanks to high-pressure capability
    • Continuous operation at up to 5000 psi when configured as a Thermo Scientific™ Reagent-Free™ IC (RFIC™) system
    • Optimized peak resolution with a choice of isocratic and electrolytic gradient separations on either channel, or optional quaternary low pressure gradients on the standard/microbore channel
    • Flexible support for standard bore (3-7mm I.D.) and microbore (1-3mm I.D.) columns on one channel and capillary columns (0.2-0.6mm I.D.) on the other
    • Wide variety of chemistries available in Thermo Scientific standard bore, microbore, capillary, and Fast IC columns
    • Flexible, easy to configure, modular design

    The capillary advantage

    The capillary channel in this hybrid system presents added advantages:

    • Always ready with 24/7 uptime and minimal calibration and equilibration time
    • Up to 18 months of continuous operation on one Eluent Generation cartridge
    • Small dead volumes for minimized peak dispersion and increased signal-to-noise ratio
    • Reduced eluent disposal costs—only 15mL/day for continuous operation at 10µL/min
    • Enhanced ease-of-use because of Thermo Scientific™ Dionex™ IC Cube™ capillary consumable cartridges
    • Choose from a broad variety of Dionex ICS-6000 modules and related products. See the Dionex ICS-6000 HPIC System Product Specifications for a full list

    Sample preparation and automation solutions

    Dionex autosamplers integrate seamlessly with all Dionex ICS-6000 HPIC systems, providing effortless automation and advanced sample preparation capabilities.


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